Publications et travaux de recherche
2025
Kléber, Mathilde; Meunier-Beillard, Nicolas; Fournel, Isabelle; Ksiazek, Eléa; Jacquier, Marine; Ecarnot, Fiona; Rigaud, Jean-Philippe; Declercq, Pierre-Louis; Quenot, Jean-Pierre; Labruyère, Marie
Dans: PLOS One, vol. 20, iss. 2, p. e0316318, 2025.
Résumé | Liens | BibTeX | Étiquettes: Covid-19
@article{Kléber2025,
title = {Barriers to and facilitators of rehabilitation according to socio-economic status, after acute respiratory distress syndrome due to COVID-19: A qualitative study in the RECOVIDS cohort},
author = {Mathilde Kléber and Nicolas Meunier-Beillard and Isabelle Fournel and Eléa Ksiazek and Marine Jacquier and Fiona Ecarnot and Jean-Philippe Rigaud and Pierre-Louis Declercq and Jean-Pierre Quenot and Marie Labruyère},
url = {https://www.researchgate.net/publication/389434833_Barriers_to_and_facilitators_of_rehabilitation_according_to_socio-economic_status_after_acute_respiratory_distress_syndrome_due_to_COVID-19_A_qualitative_study_in_the_RECOVIDS_cohort},
doi = {10.1371/journal.pone.0316318},
year = {2025},
date = {2025-02-28},
journal = {PLOS One},
volume = {20},
issue = {2},
pages = {e0316318},
abstract = {Background
The COVID-19 pandemic may have compounded social disparities in access to healthcare, with possible deleterious consequences on the functional prognosis of patients after a stay in the intensive care unit (ICU). In the previous RECOVIDS study, we reported that despite comparable pulmonary sequelae and similar access to rehabilitation, socio-economically “vulnerable” patients had lower quality of life at 6 months after an ICU stay. We aimed to describe the barriers to, and facilitators of participation in rehabilitation, among patients from the RECOVIDS study, regardless of their socio-economic situation.
Methods
Qualitative study using semi-structured interviews with adult patients admitted to ICU for PCR-proven SARS-CoV-2 infection, and who had acute respiratory distress syndrome (ARDS) or had received high flow nasal oxygen. In addition, patients had to have been living at home for the month prior to the interview and had to be proficient in French. Eligible patients were randomly selected, aiming to select the same number of socially deprived and non-socially-deprived patients. Interviews were transcribed for thematic analysis.
Results
In total, 31 interviews were performed from 10/2021 to 01/2022; 16 with socially deprived, and 15 with non-deprived participants. Average age was 65.2 (±11.6) years. Four themes emerged from the analysis of the interviews, namely: (1) the impact of the patient’s professional and socio-economic situation; (2) the feeling that age and socio-economic situation influence access to rehabilitation; (3) a perception that the healthcare system was saturated, and that inequalities exist in access to rehabilitation resources; (4) perception of previous own health and expectations of post-resuscitation health status.
Conclusion
A precarious socio-economic situation has a substantial impact on access to rehabilitation after ICU admission for ARDS caused by COVID-19. It represents a barrier to rehabilitation through the combined action of various social determinants that deserve to be detected early, in order to take appropriate action to ensure that the most socially vulnerable individuals can benefit from access to rehabilitation.},
keywords = {Covid-19},
pubstate = {published},
tppubtype = {article}
}
The COVID-19 pandemic may have compounded social disparities in access to healthcare, with possible deleterious consequences on the functional prognosis of patients after a stay in the intensive care unit (ICU). In the previous RECOVIDS study, we reported that despite comparable pulmonary sequelae and similar access to rehabilitation, socio-economically “vulnerable” patients had lower quality of life at 6 months after an ICU stay. We aimed to describe the barriers to, and facilitators of participation in rehabilitation, among patients from the RECOVIDS study, regardless of their socio-economic situation.
Methods
Qualitative study using semi-structured interviews with adult patients admitted to ICU for PCR-proven SARS-CoV-2 infection, and who had acute respiratory distress syndrome (ARDS) or had received high flow nasal oxygen. In addition, patients had to have been living at home for the month prior to the interview and had to be proficient in French. Eligible patients were randomly selected, aiming to select the same number of socially deprived and non-socially-deprived patients. Interviews were transcribed for thematic analysis.
Results
In total, 31 interviews were performed from 10/2021 to 01/2022; 16 with socially deprived, and 15 with non-deprived participants. Average age was 65.2 (±11.6) years. Four themes emerged from the analysis of the interviews, namely: (1) the impact of the patient’s professional and socio-economic situation; (2) the feeling that age and socio-economic situation influence access to rehabilitation; (3) a perception that the healthcare system was saturated, and that inequalities exist in access to rehabilitation resources; (4) perception of previous own health and expectations of post-resuscitation health status.
Conclusion
A precarious socio-economic situation has a substantial impact on access to rehabilitation after ICU admission for ARDS caused by COVID-19. It represents a barrier to rehabilitation through the combined action of various social determinants that deserve to be detected early, in order to take appropriate action to ensure that the most socially vulnerable individuals can benefit from access to rehabilitation.
2024
Launay, Pauline; Clavandier, Gaëlle; Schrecker, Cherry
Des morts dangereux à l’épreuve de l’insularité. Tensions entre soin et protection en Ehpad durant la pandémie de Covid-19 Article de journal
Dans: Socio-anthropologie, no. 50, p. 79-96, 2024.
Résumé | Liens | BibTeX | Étiquettes: Covid-19, Fin de vie
@article{Launay2024,
title = {Des morts dangereux à l’épreuve de l’insularité. Tensions entre soin et protection en Ehpad durant la pandémie de Covid-19},
author = {Pauline Launay and Gaëlle Clavandier and Cherry Schrecker},
doi = {10.4000/159uu},
year = {2024},
date = {2024-12-31},
urldate = {2024-12-31},
journal = {Socio-anthropologie},
number = {50},
pages = {79-96},
abstract = {La pandémie de Covid-19, particulièrement lors de la première vague, a profondément désorganisé les Ehpad, en exposant les résidents à un risque élevé de contagion et de décès. L’incertitude, le confinement et l’instabilité réglementaire ont bouleversé les pratiques d’accompagnement des mourants et des morts. Cet article, basé sur des entretiens, analyse la manière dont les corps des résidents contaminés ont été soumis à des mesures sanitaires strictes, plaçant les professionnels de santé face à un dilemme : (se) protéger contre le virus, ou maintenir autant que possible les pratiques jugées « bonnes » d’accompagnement des mourants et des morts. Ces deux impératifs sont parfois entrés en contradiction, créant une situation exceptionnelle. La première vague constitue en cela un cas intense et limite de tensions et d’incertitude généralisées dans l’activité de soin, du fait de la forte instabilité réglementaire et du confinement strict qui ont placé les Ehpad en situation d’insularité.},
keywords = {Covid-19, Fin de vie},
pubstate = {published},
tppubtype = {article}
}
2023
Jahier, Youna; Rabiaza, Andry; Gouriot, Mylène; Grandazzi, Guillaume; Humbert, Xavier
Ressenti des médecins généralistes français concernant la gestion par les autorités sanitaires de la pandémie liée au COVID-19 Article de journal
Dans: Médecine, vol. 19, no. 9, p. 426-431, 2023.
Résumé | Liens | BibTeX | Étiquettes: Covid-19
@article{Jahier2023,
title = {Ressenti des médecins généralistes français concernant la gestion par les autorités sanitaires de la pandémie liée au COVID-19},
author = {Youna Jahier and Andry Rabiaza and Mylène Gouriot and Guillaume Grandazzi and Xavier Humbert},
url = {https://www.jle.com/fr/revues/med/e-docs/ressenti_des_medecins_generalistes_francais_concernant_la_gestion_par_les_autorites_sanitaires_de_la_pandemie_liee_au_covid_19_333367/article.phtml},
doi = {10.1684/med.2023.932},
year = {2023},
date = {2023-11-01},
journal = {Médecine},
volume = {19},
number = {9},
pages = {426-431},
abstract = {La pandémie Covid-19 a obligé les autorités sanitaires à prendre des décisions réglementaires contraignantes. Parmi celles-ci, la restriction des consultations en médecine générale a été probablement mal vécue par la profession. Dans cette étude qualitative, les auteurs explorent le ressenti des médecins généralistes quant à la gestion de la crise par les autorités sanitaires.},
keywords = {Covid-19},
pubstate = {published},
tppubtype = {article}
}
2022
Balard, Frédéric; Caradec, Vincent; Castra, Michel; Chassagne, Aline; Clavandier, Gaëlle; Launay, Pauline; Schrecker, Cherry; Trimaille, Hélène
Life in Care Homes during the Covid-19 Pandemic. The Social Logics of the Experience of the First Confinement Article de journal
Dans: Revue des politiques sociales et familiales, vol. 4, no. 145, p. 147-163, 2022.
Résumé | Liens | BibTeX | Étiquettes: Covid-19
@article{Balard2022,
title = {Life in Care Homes during the Covid-19 Pandemic. The Social Logics of the Experience of the First Confinement},
author = {Frédéric Balard and Vincent Caradec and Michel Castra and Aline Chassagne and Gaëlle Clavandier and Pauline Launay and Cherry Schrecker and Hélène Trimaille},
doi = {10.3917/rpsf.145.0147},
year = {2022},
date = {2022-09-01},
journal = {Revue des politiques sociales et familiales},
volume = {4},
number = {145},
pages = {147-163},
abstract = {This article, based on 37 interviews with residents living in 15 care homes in France, analyses their diverse experience of the first lockdown. Firstly, we will show that the experience of the lockdown took on different forms depending on the residents’ lifestyles. For those who were used to staying in their rooms, life during the lockdown was very similar to before. Those who were used to spending time in the common areas felt deprived of their social life. Residents who were used to spending time outside their establishment emphasised the lack of freedom during the lockdown which prevented them from leaving the premises. Secondly, the article explores three key factors which influenced the reactions of residents: how lockdown was implemented within their respective care homes, the occupational background and social resources which the residents could draw on, and their previous life experience.},
keywords = {Covid-19},
pubstate = {published},
tppubtype = {article}
}
Declercq, Pierre-Louis; Fournel, Isabelle; Demeyere, Matthieu; Ksiazek, Eléa; Meunier-Beillard, Nicolas; Rivière, Antoine; Clarot, Caroline; Maizel, Julien; Schnell, David; Plantefeve, Gaetan; Ampere, Alexandre; Daubin, Cédric; Sauneuf, Bertrand; Kalfon, Pierre; Federici, Laura; Redureau, Élise; Bousta, Mehdi; Lagache, Laurie; Vanderlinden, Thierry; Nseir, Saad; Combe, Béatrice La; Bourdin, Gaël; Monchi, Mehran; Nyunga, Martine; Ramakers, Michel; Oulehri, Walid; Georges, Hugues; Gandonniere, Charlotte Salmon; Badie, Julio; Delbove, Agathe; Monnet, Xavier; Beduneau, Gaetan; Artaud-Macari, Élise; Abraham, Paul; Delberghe, Nicolas; Bouar, Gurvan Le; Miailhe, Arnaud-Felix; Hraiech, Sami; Bironneau, Vanessa; Sedillot, Nicholas; Hoppe, Marie-Anne; Barbar, Saber Davide; Calcaianu, George-Daniel; Dellamonica, Jean; Terzi, Nicolas; Delpierre, Cyrille; Gélinotte, Stéphanie; Rigaud, Jean-Philippe; Labruyère, Marie; Georges, Marjolaine; Binquet, Christine; Quenot, Jean-Pierre; trial investigators, RECOVIDS
Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2 : the multicentre observational RECOVIDS study Article de journal
Dans: BMJ Open, vol. 12, no. e057368, 2022.
Résumé | Liens | BibTeX | Étiquettes: Covid-19
@article{Declercq2022b,
title = {Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2 : the multicentre observational RECOVIDS study},
author = {Pierre-Louis Declercq and Isabelle Fournel and Matthieu Demeyere and Eléa Ksiazek and Nicolas Meunier-Beillard and Antoine Rivière and Caroline Clarot and Julien Maizel and David Schnell and Gaetan Plantefeve and Alexandre Ampere and Cédric Daubin and Bertrand Sauneuf and Pierre Kalfon and Laura Federici and Élise Redureau and Mehdi Bousta and Laurie Lagache and Thierry Vanderlinden and Saad Nseir and Béatrice La Combe and Gaël Bourdin and Mehran Monchi and Martine Nyunga and Michel Ramakers and Walid Oulehri and Hugues Georges and Charlotte Salmon Gandonniere and Julio Badie and Agathe Delbove and Xavier Monnet and Gaetan Beduneau and Élise Artaud-Macari and Paul Abraham and Nicolas Delberghe and Gurvan Le Bouar and Arnaud-Felix Miailhe and Sami Hraiech and Vanessa Bironneau and Nicholas Sedillot and Marie-Anne Hoppe and Saber Davide Barbar and George-Daniel Calcaianu and Jean Dellamonica and Nicolas Terzi and Cyrille Delpierre and Stéphanie Gélinotte and Jean-Philippe Rigaud and Marie Labruyère and Marjolaine Georges and Christine Binquet and Jean-Pierre Quenot and RECOVIDS trial investigators},
url = {https://bmjopen.bmj.com/content/12/4/e057368},
doi = {10.1136/bmjopen-2021-057368},
year = {2022},
date = {2022-04-04},
journal = {BMJ Open},
volume = {12},
number = {e057368},
abstract = {Introduction
Prognosis of patients with COVID-19 depends on the severity of the pulmonary affection. The most severe cases may progress to acute respiratory distress syndrome (ARDS), which is associated with a risk of long-term repercussions on respiratory function and neuromuscular outcomes. The functional repercussions of severe forms of COVID-19 may have a major impact on quality of life, and impair the ability to return to work or exercise. Social inequalities in healthcare may influence prognosis, with socially vulnerable individuals more likely to develop severe forms of disease. We describe here the protocol for a prospective, multicentre study that aims to investigate the influence of social vulnerability on functional recovery in patients who were hospitalised in intensive care for ARDS caused by COVID-19. This study will also include an embedded qualitative study that aims to describe facilitators and barriers to compliance with rehabilitation, describe patients’ health practices and identify social representations of health, disease and care.
Methods and analysis
The "Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status" (RECOVIDS) study is a mixed-methods, observational, multicentre cohort study performed during the routine follow-up of post-intensive care unit (ICU) functional recovery after ARDS. All patients admitted to a participating ICU for PCR-proven SARS-CoV-2 infection and who underwent chest CT scan at the initial phase AND who received respiratory support (mechanical or not) or high-flow nasal oxygen, AND had ARDS diagnosed by the Berlin criteria will be eligible. The primary outcome is the presence of lung sequelae at 6 months after ICU discharge, defined either by alterations on pulmonary function tests, oxygen desaturation during a standardised 6 min walk test or fibrosis-like pulmonary findings on chest CT. Patients will be considered to be socially disadvantaged if they have an "Evaluation de la Précarité et des Inégalités de santé dans les Centres d’Examen de Santé" (EPICES) score ≥30.17 at inclusion.
Ethics and dissemination
The study protocol and the informed consent form were approved by an independent ethics committee (Comité de Protection des Personnes Sud Méditerranée II) on 10 July 2020 (2020-A02014-35). All patients will provide informed consent before participation. Findings will be published in peer-reviewed journals and presented at national and international congresses.},
keywords = {Covid-19},
pubstate = {published},
tppubtype = {article}
}
Prognosis of patients with COVID-19 depends on the severity of the pulmonary affection. The most severe cases may progress to acute respiratory distress syndrome (ARDS), which is associated with a risk of long-term repercussions on respiratory function and neuromuscular outcomes. The functional repercussions of severe forms of COVID-19 may have a major impact on quality of life, and impair the ability to return to work or exercise. Social inequalities in healthcare may influence prognosis, with socially vulnerable individuals more likely to develop severe forms of disease. We describe here the protocol for a prospective, multicentre study that aims to investigate the influence of social vulnerability on functional recovery in patients who were hospitalised in intensive care for ARDS caused by COVID-19. This study will also include an embedded qualitative study that aims to describe facilitators and barriers to compliance with rehabilitation, describe patients’ health practices and identify social representations of health, disease and care.
Methods and analysis
The "Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status" (RECOVIDS) study is a mixed-methods, observational, multicentre cohort study performed during the routine follow-up of post-intensive care unit (ICU) functional recovery after ARDS. All patients admitted to a participating ICU for PCR-proven SARS-CoV-2 infection and who underwent chest CT scan at the initial phase AND who received respiratory support (mechanical or not) or high-flow nasal oxygen, AND had ARDS diagnosed by the Berlin criteria will be eligible. The primary outcome is the presence of lung sequelae at 6 months after ICU discharge, defined either by alterations on pulmonary function tests, oxygen desaturation during a standardised 6 min walk test or fibrosis-like pulmonary findings on chest CT. Patients will be considered to be socially disadvantaged if they have an "Evaluation de la Précarité et des Inégalités de santé dans les Centres d’Examen de Santé" (EPICES) score ≥30.17 at inclusion.
Ethics and dissemination
The study protocol and the informed consent form were approved by an independent ethics committee (Comité de Protection des Personnes Sud Méditerranée II) on 10 July 2020 (2020-A02014-35). All patients will provide informed consent before participation. Findings will be published in peer-reviewed journals and presented at national and international congresses.
2021
Pouget-Abadie, Jean-François
Vivre la pandémie Covid 19 ou le refus de la polémique et le choix de l’éthique Article de journal
Dans: Revue de bioéthique de Nouvelle-Aquitaine, no. 8, p. 55-60, 2021.
Résumé | Liens | BibTeX | Étiquettes: Covid-19
@article{Pouget-Abadie2021b,
title = {Vivre la pandémie Covid 19 ou le refus de la polémique et le choix de l’éthique},
author = {Jean-François Pouget-Abadie},
url = {https://hal.science/hal-03325269/document},
year = {2021},
date = {2021-08-05},
urldate = {2021-08-05},
journal = {Revue de bioéthique de Nouvelle-Aquitaine},
number = {8},
pages = {55-60},
abstract = {Le récit de l’irruption redoutée de la Covid 19 dans un Ehpad est suivi d’un témoignage du vécu et du ressenti de l’auteur, médecin, confronté aux difficultés et aux souffrances apportées par une pandémie qui semble s’éterniser. Au moyen de quelques exemples, les polémiques sont dénoncées car elles sont nombreuses et obscurcissent le champ de l’information. La réflexion éthique est déclarée indispensable. },
keywords = {Covid-19},
pubstate = {published},
tppubtype = {article}
}
Gatti, Laurence; Raoul-Cormeil, Gilles
Covid-19 : le consentement à l’acte vaccinal des majeurs vulnérables ou l’éprouvante réception du régime des décisions de santé des majeurs protégés Article de journal
Dans: Revue Générale de Droit Médical, no. 78, p. 121-140, 2021.
Résumé | Liens | BibTeX | Étiquettes: Covid-19, Vaccination
@article{Gatti2021,
title = {Covid-19 : le consentement à l’acte vaccinal des majeurs vulnérables ou l’éprouvante réception du régime des décisions de santé des majeurs protégés},
author = {Laurence Gatti and Gilles Raoul-Cormeil},
url = {https://www.bnds.fr/edition-numerique/revue/rgdm/rgdm-78/covid-19-le-consentement-a-l-acte-vaccinal-des-majeurs-vulnerables-ou-l-eprouvante-reception-du-regime-des-decisions-de-sante-des-majeurs-proteges-10570.html},
year = {2021},
date = {2021-03-01},
urldate = {2021-03-01},
journal = {Revue Générale de Droit Médical},
number = {78},
pages = {121-140},
abstract = {Toutes les personnes bénéficiant d’une mesure de protection juridique ne sont pas aptes à consentir à l’acte vaccinal contre le coronavirus ou SARS-CoV-2. Il en est de même parmi les personnes du grand âge résidant en EHPAD. Face à cette difficulté considérable, le ministre des Solidarités et de la Santé a saisi le Conseil consultatif national d’éthique. Son avis du 18 décembre 2020 et les nombreux documents émanant des EHPAD que nous ont transmis les mandataires judiciaires à la protection des majeurs révèlent leur méconnaissance du droit applicable à la relation de soin du majeur protégé. Il est donc utile de rappeler l’esprit et la lettre de l’ordonnance du 11 mars 2020, entrée en vigueur le 1er octobre 2020, et de confronter les règles nouvelles, respectueuses de l’autonomie de la personne vulnérable, aux remèdes envisagés lorsque la personne protégée est inapte à consentir seule à un acte médical. En éthique et en responsabilité, les mandataires judiciaires à la protection des majeurs, les professionnels de santé et les cadres des EHPAD doivent travailler sur cette base commune.},
keywords = {Covid-19, Vaccination},
pubstate = {published},
tppubtype = {article}
}
2020
Eustache-Vallée, Marie-Loup
Vivre une période de confinement pour les patients Alzheimer en Résidence pour personnes âgées dépendantes Article de journal
Dans: Revue de neuropsychologie, vol. 12, no. 2, p. 171-174, 2020.
Liens | BibTeX | Étiquettes: Covid-19, Gérontologie
@article{Eustache-Vallée2020,
title = {Vivre une période de confinement pour les patients Alzheimer en Résidence pour personnes âgées dépendantes},
author = {Marie-Loup Eustache-Vallée},
doi = {10.1684/nrp.2020.0562},
year = {2020},
date = {2020-09-01},
urldate = {2020-09-01},
journal = {Revue de neuropsychologie},
volume = {12},
number = {2},
pages = {171-174},
keywords = {Covid-19, Gérontologie},
pubstate = {published},
tppubtype = {article}
}
de Champs Léger, Hélène; Moutel, Grégoire
Principes de justice et de responsabilité : regard sur l’accès aux soins avant, pendant et après la crise du Covid Article de journal
Dans: La Revue du Praticien, vol. 70, no. 4, p. 377-378, 2020.
Liens | BibTeX | Étiquettes: Covid-19
@article{deLéger2020,
title = {Principes de justice et de responsabilité : regard sur l’accès aux soins avant, pendant et après la crise du Covid},
author = { Hélène de Champs Léger and Grégoire Moutel },
editor = {La revue du praticien},
url = {https://www.larevuedupraticien.fr/dossier/principes-de-justice-et-de-responsabilite-regard-sur-lacces-aux-soins-avant-pendant-et},
year = {2020},
date = {2020-04-01},
urldate = {2020-04-01},
journal = {La Revue du Praticien},
volume = {70},
number = {4},
pages = {377-378},
keywords = {Covid-19},
pubstate = {published},
tppubtype = {article}
}